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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rpmj</journal-id><journal-title-group><journal-title xml:lang="ru">Research'n Practical Medicine Journal</journal-title><trans-title-group xml:lang="en"><trans-title>Research and Practical Medicine Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2410-1893</issn><publisher><publisher-name>"QUASAR", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17709/2410-1893-2025-12-2-5</article-id><article-id custom-type="edn" pub-id-type="custom">DPJNBH</article-id><article-id custom-type="elpub" pub-id-type="custom">rpmj-1106</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Articles</subject></subj-group></article-categories><title-group><article-title>Хирургическая патология щитовидной железы в Республике Крым и городе Севастополе: как пандемия COVID-19 изменила структуру заболеваемости</article-title><trans-title-group xml:lang="en"><trans-title>Surgical thyroid pathology in Crimea and Sevastopol: the way COVID-19 pandemic altered the frequency and structure of diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7795-5882</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хабаров</surname><given-names>О. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Khabarov</surname><given-names>O. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p><p>Хабаров Олег Робертович – ассистент кафедры многопрофильной клинической подготовки филиала Ордена Трудового Красного Знамени Медицинского института им. С. И. Георгиевского ФГАОУ ВО «Крымский федеральный университет им. В. И. Вернадского», г. Симферополь, Республика Крым, Российская Федерация</p><p>ORCID: <ext-link xlink:href="https://orcid.org/0000-0001-7795-5882" ext-link-type="uri">https://orcid.org/ 0000-0001-7795-5882 </ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1220987" ext-link-type="uri">8873-7706</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1220987" ext-link-type="uri">1220987</ext-link></p></bio><bio xml:lang="en"><p> </p><p>Oleg R. Khabarov – assistant of The Department of multidisciplinary clinical training, S.I. Georgievsky Medical Institute, V.I. Vernadsky Crimean Federal University, Simferopol, Republic of Crimea, Russian Federation</p><p>ORCID: <ext-link xlink:href="https://orcid.org/0000-0001-7795-5882" ext-link-type="uri">https://orcid.org/ 0000-0001-7795-5882 </ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1220987" ext-link-type="uri">8873-7706</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1220987" ext-link-type="uri">1220987</ext-link></p></bio><email xlink:type="simple">khabar.68@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4732-0311</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зима</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zima</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p><p>Зима Дмитрий Владимирович – к.м.н., врач-хирург Клинического медицинского многопрофильного центра Святителя Луки (структурное подразделение) ФГАОУ ВО «Крымский федеральный университет им. В. И. Вернадского», г. Симферополь, Республика Крым, Российская Федерация</p><p>ORCID: <ext-link xlink:href="https://orcid.org/0000-0003-4732-0311" ext-link-type="uri">https://orcid.org/0000-0003-4732-0311</ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1169223" ext-link-type="uri">6817-1090</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1169223" ext-link-type="uri">1169223</ext-link></p><p>Scopus Author ID: <ext-link xlink:href="https://www.scopus.com/authid/detail.uri?authorId=57211315756" ext-link-type="uri">57211315756</ext-link></p></bio><bio xml:lang="en"><p> </p><p>Dmitry V. Zima – Cand. Sci. (Medicine), surgeon, St. Luke Clinical Medical Multidisciplinary Center (structural unit), V.I. Vernadsky Crimean Federal University, Simferopol, Republic of Crimea, Russian Federation</p><p>ORCID: <ext-link xlink:href="https://orcid.org/0000-0003-4732-0311" ext-link-type="uri">https://orcid.org/0000-0003-4732-0311</ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1169223" ext-link-type="uri">6817-1090</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1169223" ext-link-type="uri">1169223</ext-link></p><p>Scopus Author ID: <ext-link xlink:href="https://www.scopus.com/authid/detail.uri?authorId=57211315756" ext-link-type="uri">57211315756</ext-link></p></bio><email xlink:type="simple">dmitrii_zima@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0161-8959</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Безруков</surname><given-names>О. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Bezrukov</surname><given-names>O. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p><p>Безруков Олег Филиппович – д.м.н., заведующий хирургическим отделением Клинического медицинского многопрофильного центра Святителя Луки (структурное подразделение) ФГАОУ ВО «Крымский федеральный университет им. В. И. Вернадского», г. Симферополь, Республика Крым, Российская Федерация</p><p>ORCID: <ext-link xlink:href="https://orcid.org/0000-0002-0161-8959" ext-link-type="uri">https://orcid.org/0000-0002-0161-8959</ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=770782" ext-link-type="uri">7517-1950</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=770782" ext-link-type="uri">770782</ext-link></p><p>Scopus Author ID: <ext-link xlink:href="https://www.scopus.com/authid/detail.uri?authorId=6601945153" ext-link-type="uri">6601945153</ext-link></p></bio><bio xml:lang="en"><p> </p><p>Oleg F. Bezrukov – Dr. Sci. (Medicine), Head of the Surgical Department, St. Luke Clinical Medical Multidisciplinary Center (structural unit), V.I. Vernadsky Crimean Federal University, Simferopol, Republic of Crimea, Russian Federation</p><p>ORCID: <ext-link xlink:href="https://orcid.org/0000-0002-0161-8959" ext-link-type="uri">https://orcid.org/0000-0002-0161-8959</ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=770782" ext-link-type="uri">7517-1950</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=770782" ext-link-type="uri">770782</ext-link></p><p>Scopus Author ID: <ext-link xlink:href="https://www.scopus.com/authid/detail.uri?authorId=6601945153" ext-link-type="uri">6601945153</ext-link></p></bio><email xlink:type="simple">klinika_csmu@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8216-4196</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зяблицкая</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zyablitskaya</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p><p>Зяблицкая Евгения Юрьевна – д.м.н., доцент, ведущий научный сотрудник Центральной научно-исследовательской лаборатории Ордена Трудового Красного Знамени Медицинского института им. С. И. Георгиевского ФГАОУ ВО «Крымский федеральный университет им. В. И. Вернадского», г. Симферополь, Республика Крым, Российская Федерация</p><p>ORCID: <ext-link xlink:href="https://orcid.org/0000-0001-8216-4196" ext-link-type="uri">https://orcid.org/0000-0001-8216-4196</ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_items.asp?authorid=766290" ext-link-type="uri">2267-3643</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_items.asp?authorid=766290" ext-link-type="uri">766290</ext-link></p><p>Scopus Author ID: <ext-link xlink:href="https://www.scopus.com/authid/detail.uri?authorId=57220137811" ext-link-type="uri">57220137811</ext-link></p><p>Web of Science ResearcherID: <ext-link xlink:href="https://www.webofscience.com/wos/author/record/Q-2890-2017" ext-link-type="uri">Q-2890-2017</ext-link></p></bio><bio xml:lang="en"><p> </p><p>Evgeniya Yu. Zyablitskaya – Dr. Sci. (Medicine), Associate Professor, Leading Researcher at the Central Research Laboratory, S.I. Georgievsky Medical Institute, V.I. Vernadsky Crimean Federal University, Simferopol, Republic of Crimea, Russian Federation</p><p>ORCID: <ext-link xlink:href="https://orcid.org/0000-0001-8216-4196" ext-link-type="uri">https://orcid.org/0000-0001-8216-4196</ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_items.asp?authorid=766290" ext-link-type="uri">2267-3643</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_items.asp?authorid=766290" ext-link-type="uri">766290</ext-link></p><p>Scopus Author ID: <ext-link xlink:href="https://www.scopus.com/authid/detail.uri?authorId=57220137811" ext-link-type="uri">57220137811</ext-link></p><p>Web of Science ResearcherID: <ext-link xlink:href="https://www.webofscience.com/wos/author/record/Q-2890-2017" ext-link-type="uri">Q-2890-2017</ext-link></p></bio><email xlink:type="simple">evgu79@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-0409-3297</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Асанова</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Asanova</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p><p>Асанова Эльвина Рефатовна – младший научный сотрудник Центральной научно-исследовательской лаборатории Ордена Трудового Красного Знамени Медицинского института им. С. И. Георгиевского ФГАОУ ВО «Крымский федеральный университет им. В. И. Вернадского», г. Симферополь, Республика Крым, Российская Федерация</p><p>ORCID: <ext-link xlink:href="http://orcid.org/0009-0001-0409-3297" ext-link-type="uri">http://orcid.org/0009-0001-0409-3297</ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1210039" ext-link-type="uri">8110-7701</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1210039" ext-link-type="uri">1210039</ext-link></p><p>Scopus Author ID: <ext-link xlink:href="https://www.scopus.com/authid/detail.uri?authorId=59389556600" ext-link-type="uri">59389556600</ext-link></p></bio><bio xml:lang="en"><p> </p><p>Elvina R. Asanova – Junior Researcher of the Central Research Laboratory, S.I. Georgievsky Medical Institute, V.I. Vernadsky Crimean Federal University, Simferopol, Republic of Crimea, Russian Federation</p><p>ORCID: <ext-link xlink:href="http://orcid.org/0009-0001-0409-3297" ext-link-type="uri">http://orcid.org/0009-0001-0409-3297</ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1210039" ext-link-type="uri">8110-7701</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1210039" ext-link-type="uri">1210039</ext-link></p><p>Scopus Author ID: <ext-link xlink:href="https://www.scopus.com/authid/detail.uri?authorId=59389556600" ext-link-type="uri">59389556600</ext-link></p></bio><email xlink:type="simple">elyabiolog@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5920-8664</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимова</surname><given-names>П. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimova</surname><given-names>P. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p><p>Максимова Полина Евгеньевна – младший научный сотрудник Центральной научно-исследовательской лаборатории Ордена Трудового Красного Знамени Медицинского института им. С. И. Георгиевского ФГАОУ ВО «Крымский федеральный университет им. В. И. Вернадского», г. Симферополь, Республика Крым, Российская Федерация</p><p>ORCID: <ext-link xlink:href="http://orcid.org/0000-0001-5920-8664" ext-link-type="uri">http://orcid.org/0000-0001-5920-8664</ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1156001" ext-link-type="uri">9734-8508</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1156001" ext-link-type="uri">1156001</ext-link></p><p>Scopus Author ID: <ext-link xlink:href="https://www.scopus.com/authid/detail.uri?authorId=57298383500" ext-link-type="uri">57298383500</ext-link></p></bio><bio xml:lang="en"><p> </p><p>Polina E. Maksimova – Junior Researcher of the Central Research Laboratory, S.I. Georgievsky Medical Institute, V.I. Vernadsky Crimean Federal University, Simferopol, Republic of Crimea, Russian Federation</p><p>ORCID: <ext-link xlink:href="http://orcid.org/0000-0001-5920-8664" ext-link-type="uri">http://orcid.org/0000-0001-5920-8664</ext-link></p><p>eLibrary SPIN: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1156001" ext-link-type="uri">9734-8508</ext-link>, AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=1156001" ext-link-type="uri">1156001</ext-link></p><p>Scopus Author ID: <ext-link xlink:href="https://www.scopus.com/authid/detail.uri?authorId=57298383500" ext-link-type="uri">57298383500</ext-link></p></bio><email xlink:type="simple">pmaksq@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Крымский федеральный университет им. В. И. Вернадского &lt;p&gt;&#13;
г. Симферополь, Республика Крым, Российская Федерация</institution></aff><aff xml:lang="en"><institution>V.I. Vernadsky Crimean Federal University &lt;p&gt;&#13;
Simferopol, Republic of Crimea, Russian Federation</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>16</day><month>06</month><year>2025</year></pub-date><volume>12</volume><issue>2</issue><fpage>60</fpage><lpage>69</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хабаров О.Р., Зима Д.В., Безруков О.Ф., Зяблицкая Е.Ю., Асанова Э.Р., Максимова П.Е., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Хабаров О.Р., Зима Д.В., Безруков О.Ф., Зяблицкая Е.Ю., Асанова Э.Р., Максимова П.Е.</copyright-holder><copyright-holder xml:lang="en">Khabarov O.R., Zima D.V., Bezrukov O.F., Zyablitskaya E.Y., Asanova E.R., Maksimova P.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpmj.ru/rpmj/article/view/1106">https://www.rpmj.ru/rpmj/article/view/1106</self-uri><abstract><p>Цель исследования. Оценить влияние пандемии COVID-19 на структуру хирургической патологии щитовидной железы у населения Республики Крым и города Севастополя в 2019–2024 гг. на основе ретроспективного анализа данных.Пациенты и методы. Проведен ретроспективный анализ данных (историй болезни пациентов, электронных баз данных). Пациенты были разделены на 4 группы: поступившие в хирургический стационар до, во время и после пандемии COVID-19 (ранний и отдаленный периоды). Проанализировано 1038 случаев (684 – Республика Крым, 354 – город Севастополь). В анализ были включены данные гистологических исследований операционного материала. Данные обработаны в StatTech v. 4.7.1. Использованы хи-квадрат Пирсона (с поправкой Холма) и V Крамера. Различия статистически значимы при p &lt; 0,05.Результаты. Проведенный анализ данных за 2019–2024 гг. выявил значительные изменения в структуре хирургической патологии щитовидной железы в Республике Крым и городе Севастополе. В постпандемический период отмечен рост доли злокачественных новообразований: в Крыму частота рака щитовидной железы увеличилась на 9,8–11,5 % (p &lt; 0,05), в Севастополе – на 9,8–33,5 % (p &lt; 0,001). Доминировал папиллярный рак, доля которого в Крыму выросла с 24,7 % до 31,0 %, а в Севастополе достигла 57,6 % среди всей патологии щитовидной железы, требующей хирургического лечения. В Крыму зафиксировано увеличение метастазирования в лимфатические узлы (до 38,6 %, p &lt; 0,05) и капсулярной инвазии (26,3 %, p &lt; 0,001), тогда как в Севастополе во время пандемии участились случаи мультицентрического роста (31,9 %, p &lt; 0,05). Рост встречаемости токсического зоба в общей структуре патологии отмечен в пик пандемии (в Крыму – с 10,8 % до 26,6 %; в Севастополе – с 1,6 % до 11,7 %) с последующей нормализацией к 2024 г. Гендерный анализ подтвердил преобладание женщин среди пациентов (85–92 %), особенно в менопаузальном периоде.Заключение. Пандемия COVID-19 привела к отсроченной диагностике и росту агрессивных форм рака щитовидной железы, что связано с ограничением плановой помощи и прямым воздействием вируса на ткань. Рост доли агрессивных форм рака щитовидной железы, включая метастазирование и инвазивные подтипы, связан с отсрочкой плановых операций и скрининга в период ограничений, что в свою очередь требует усиления скрининговых программ. Полученные данные указывают на важность адаптации системы здравоохранения к глобальным кризисам, включая ресурсы онкологической помощи, а также алгоритмы ранней диагностики.</p></abstract><trans-abstract xml:lang="en"><p>Purpose of the study. To evaluate the impact of the COVID-19 pandemic on the structure of surgical thyroid pathology among the population of the Republic of Crimea and Sevastopol City in 2019–2024 through a retrospective data analysis.Patients and methods. A retrospective analysis of the data (patient medical records, electronic databases) was carried out. Patients were divided into four groups: pre-pandemic, pandemic, and post-pandemic (early and late periods). A total of 1038 cases were analyzed (684 from Crimea, 354 from Sevastopol). Only histological data from surgical specimens were included. Statistical analysis was performed using StatTech v. 4.7.1, applying Pearson’s chi-square (with Holm correction) and Cramer’s V tests. Differences were considered statistically significant at p &lt; 0.05.Results. Analysis of 2019–2024 data revealed significant changes in the structure of surgical thyroid pathology in Crimea and Sevastopol. The post-pandemic period had an increased proportion of malignant neoplasms: thyroid cancer frequency in Crimea rose by 9.8–11.5 % (p &lt; 0.05) and in Sevastopol by 9.8–33. 5 % (p &lt; 0.001). Papillary carcinoma became dominant, increasing from 24.7 % to 31.0 % in Crimea and reaching 57.6 % in Sevastopol. Crimea recorded higher lymph node metastasis (up to 38.6 %,  p = 0.003) and capsular invasion (26.3 %, p &lt; 0.001), while Sevastopol showed multicentric tumor growth during the pandemic (31.9 %, p = 0.003). A surge in toxic goiter at the pandemic peak (Crimea: 10.8 % to 26.6 %; Sevastopol: 1.6 % to 11.7 %) normalized by 2024. Gender analysis confirmed women’s predominance among patients (85–92 %), particularly in the menopausal period.Conclusion. The COVID-19 pandemic caused delayed diagnosis and increased aggressive thyroid cancer forms, linked to restricted routine care and the virus’s direct impact on thyroid tissue. The rise in aggressive thyroid cancer subtypes, including metastatic and invasive forms, reflects postponed surgeries and screening during restrictions, underscoring the need for enhanced screening programs. These findings highlight the importance of adapting healthcare systems to global crises, including reserving resources for oncology care and developing early diagnostic algorithms.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>рак щитовидной железы</kwd><kwd>папиллярная карцинома</kwd><kwd>диагностика</kwd><kwd>гендерные различия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>thyroid cancer</kwd><kwd>papillary carcinoma</kwd><kwd>delayed diagnosis</kwd><kwd>gender disparities</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">работа проведена при финансовой поддержке государственного задания FZEG-2023-0009 «Изучение гетерогенности микроокружения опухоли как фактора ее агрессивности и резистентности к терапии».</funding-statement><funding-statement xml:lang="en">the work was carried out with the financial support of the state task FZEG-2023-0009 "Study of heterogeneity of the tumor microenvironment as a factor of its aggressiveness and resistance to therapy"</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nadarajan AR, George NA, Thomas S, Varghese BT, Iype EM, K M JK. 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