rpmjResearch'n Practical Medicine JournalResearch and Practical Medicine Journal2410-1893"QUASAR", LLC10.17709/2409-2231-2017-4-1-5rpmj-171Research ArticleОбзорыReviewСОВРЕМЕННЫЕ ВОЗМОЖНОСТИ МАГНИТНО-РЕЗОНАНСНОЙ ТОМОГРАФИИ В ДИАГНОСТИКЕ РАКА ЯИЧНИКОВCURRENT POSSIBILITIES OF MAGNETIC – RESONANCE IMAGING IN DETECTION OF OVARIAN CANCERРубцоваН. А.RubtsovaN. A.

д.м.н., руководитель отдела лучевой диагностики,

125284, Москва, 2-й Боткинский проезд, 3

MD. Med., the Head of Radiology Department,

3, 2nd Botkinskiy proezd, Moscow, 125284

RNA17@yandex.ruНовиковаЕ. Г.NovikovaE. G.

д.м.н., профессор, руководитель отделения онкогинекологии,

125284, Москва, 2-й Боткинский проезд, 3

MD. Med., professor, Head of Oncogynecological Department,

3, 2nd Botkinskiy proezd, Moscow, 125284

egnov@bk.ruСыченковаИ. Ю.SychenkovaI. Yu.

врач-рентгенолог отдела лучевой диагностики,

125284, Москва, 2-й Боткинский проезд, 3

radiologyst,

3, 2nd Botkinskiy proezd, Moscow, 125284

sichiu@rambler.ruМосковский научно-исследовательский онкологический институт им. П.А. Герцена – филиал ФБГУ «Национальный медицинский исследовательский радиологический центр» Минздрава РоссииРоссияP. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationRussian Federation201723032017414048Copyright © Рубцова Н.А., Новикова Е.Г., Сыченкова И.Ю., 20172017Рубцова Н.А., Новикова Е.Г., Сыченкова И.Ю.Rubtsova N.A., Novikova E.G., Sychenkova I.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rpmj.ru/rpmj/article/view/171

настоящее время злокачественные новообразования яичников находятся на третьем месте в структуре онкогинекологической заболеваемости, являясь при этом ведущей причиной смерти среди заболеваний женской репродуктивной системы. Ввиду отсутствия эффективных скрининговых программ и асимптомности течения болезни на ранних стадиях, у большинства больных рак яичников (РЯ) выявляется в диссеминированной форме, что существенно снижает эффективность первичного лечения и оказывает отрицательное влияние на дальнейший прогноз заболевания. В связи с вышесказанным своевременная диагностика и организация скрининга РЯ, а также тщательного мониторинга его рецидивов является важнейшей задачей для онкологов всего мира.

В представленном литературном обзоре рассмотрен опыт применения магнитно-резонансной томографии (МРТ) в диагностике первичного РЯ и его рецидивов, проведен анализ диагностической эффективности метода с учетом применения различных методик. Возможности МРТ на сегодняшний день позволяют получить значительный объем информации, необходимой для характеристики выявленных образований яичников, оценки распространенности первичного РЯ и его рецидивов. Однако выполненный анализ сведений литературы выявил существенный недостаток работ, посвященных определению диагностических возможностей различных методик МРТ, в том числе диффузионно-взвешенных изображений (ДВИ), что свидетельствует о необходимости проведения дальнейших широкомасштабных исследований в данном направлении.

Currently, malignant tumors of ovaries take the third place in the structure of oncogynecological diseases, being a leading cause of death among pathology of female reproductive system. Due to the lack of effective screening programs and asymptomatic course of the disease in its early stages, in the majority of cases ovarian cancer (OC) is detected in form of disseminated process, what greatly reduces the effectiveness of primary treatment and has a negative impact on the further prognosis. In connection with the above, timely diagnosis and organization of OC screening, as well as monitoring of its recurrence is a major problem for oncologists around the world.

In the present literature review the opportunities of magnetic — resonance imaging (MRI) in detection of primary ovarian cancer and its recurrence are considered, the analysis of the method diagnostic efficiency based on the use of various techniques is done. The opportunities of MRI show a lot of information necessary for the characterization of detected ovarian formations, estimates of the prevalence of primary ovarian cancer and its recurrence. However, the analysis of performed literature revealed a significant lack of materials devoted to the definition of the diagnostic capabilities of various MRI techniques, including diffusion — weighted imaging (DWI), what indicates the necessity for further studies in this direction.

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The authors declare that there are no conflicts of interest present.