rpmjResearch'n Practical Medicine JournalResearch and Practical Medicine Journal2410-1893"QUASAR", LLC10.17709/2409-2231-2019-6-1-7rpmj-360Research ArticleОбзорыReviewФОТОДИНАМИЧЕСКАЯ ТЕРАПИЯ БОЛЬНЫХ РАКОМ ПРОКСИМАЛЬНЫХ ВНЕПЕЧЕНОЧНЫХ ЖЕЛЧНЫХ ПРОТОКОВPHOTODYNAMIC THERAPY IN PATIENTS WITH HILAR CHOLANGIOCARCINOMAМосквичеваЛ. И.MoskvichevaL. I.

врач-онколог кабинета ультразвуковой диагностики и терапии

125284, Российская Федерация, г. Москва, 2-й Боткинский проезд, д. 3

oncologist of the ultrasound department

3, 2nd Botkinskiy proezd, Moscow, 125284, Russian Federation

ludamed16@mail.ruМосковский научно-исследовательский онкологический институт им. П.А.Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии»РоссияP.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological CentreRussian Federation201904042019617582Copyright © Москвичева Л.И., 20192019Москвичева Л.И.Moskvicheva L.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rpmj.ru/rpmj/article/view/360

Рак внепеченочных желчных протоков является одной из тех патологий, при которых порядка 70% больных в силу распространенности опухолевого процесса не могут получить радикального лечения, что определяет необходимость активного внедрения в практику методов, позволяющих при сохранении удовлетворительного качества жизни пациентов увеличить показатели выживаемости.В связи с особенностями локализации и развития злокачественных новообразований внепеченочных желчных протоков, а также характера течения заболевания особое значение в терапии данных пациентов придается различным методикам наружного или внутреннего желчеотведения, при успешном выполнении которых вторым этапом лечения могут быть рассмотрены локальные или системные методы воздействия.В настоящее время в качестве методов местной терапии у больных нерезектабельным раком внепеченочных желчных протоков используют различные варианты лучевой терапии, радиочастотную и микроволновую абляцию, фотодинамическую терапию.В настоящей статье представлен литературный обзор, освещающий техническую  возможность, безопасность и эффективность применения фотодинамической терапии у больных раком проксимальных внепеченочных желчных протоков.

Extrahepatic bile duct cancer is one of those pathologies in which about 70% of patients due to the prevalence of the tumor process can not receive radical treatment, which determines the need for active implementation of methods that allow, while maintaining a satisfactory quality of life of patients, to increase survival rates.Due to the peculiarities of localization and development of malignant tumors of the extrahepatic bile ducts, as well as the nature of the disease, special importance in the treatment of these patients is given to various methods of external or internal bile removal and on the second stage of treatment can be considered local or systemic methods of exposure.Currently, as a method of local therapy in patients with unresectable extrahepatic bile duct cancer, various options of radiation therapy, radiofrequency and microwave ablation, photodynamic therapy are used.This article presents a literature review covering the feasibility, safety and efficacy of photodynamic therapy in patients with Klatskin tumor.

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The authors declare that there are no conflicts of interest present.