rpmjResearch'n Practical Medicine JournalResearch and Practical Medicine Journal2410-1893"QUASAR", LLC10.17709/2409-2231-2019-6-2-10rpmj-404Research ArticleОбзорReviewНЕСАХАРНЫЙ ДИАБЕТ: МАЛОИЗВЕСТНЫЕ ФАКТЫDIABETES INSIPIDUS: LITTLE-KNOWN FACTShttps://orcid.org/0000-0002-6608-2825МоргуновЛ. Ю.MorgunovL. Yu.

д.м.н., профессор кафедры госпитальной терапии с курсом эндокринологии, гематологии и клинической лабораторной диагностики; заведующий эндокринологическим отделением 

117198, г. Москва, ул. Миклухо-Маклая, д. 6 ; 129327, г. Москва, ул. Ленская, д. 15

MD, PhD, DSc, professor of the department of hospital therapy with a course in endocrinology, hematology and clinical laboratory diagnostics; , head of endocrinology department

 6 Miklukho-Maklaja str., Moscow 117198; 15 Lenskaya str., Moscow 129327

Медицинский институт ФГАОУ ВО «Российский университет дружбы народов» ; ГБУЗ «Городская клиническая больница им. А.К. Ерамишанцева» Департамента здравоохранения г. МосквыРоссияMedical Institute of Peoples' Friendship University of Russia (RUDN University); A.K.Eramishantsev City Clinical Hospital, Department of Health of MoscowRussian Federation20192706201962100109Copyright © Моргунов Л.Ю., 20192019Моргунов Л.Ю.Morgunov L.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rpmj.ru/rpmj/article/view/404

Наиболее частыми причинами несахарного диабета являются нейрохирургические операции на гипофизе вследствие его поражения доброкачественными и злокачественными опухолями, сами новообразования, лимфоцитарный гипофизит. Значительно меньше известно о развитии метастатического поражения гипофиза первичными опухолями легких, молочной железы и почек. Еще реже встречается несахарный диабет, обусловленный лейкозами, лимфомой, ксантогранулемами, герминомой, ВИЧ-инфекцией, кровоизлиянием в гипофиз, лекарственно-индуцированный, сочетающийся с нейрофиброматозом, а также атипичный гестагенный. В обзоре описаны предикторы развития несахарного диабета при оперативных вмешательствах, частота развития и прогноз при различных нейрохирургических операциях. Статья ориентирует врачей различных специальностей на своевременную диагностику, профилактику и лечение несахарного диабета, в том числе его нетипичных форм.

The most common causes of diabetes insipidus are neurosurgical operations on the pituitary gland due to its defeat by benign and malignant tumors, the neoplasms themselves, lymphocytic hypophysitis. Much less is known about the development of metastatic lesions of the pituitary gland by primary tumors of the lung, breast and kidneys. Even less common is diabetes insipidus caused by leukemia, lymphoma, xanthogranulomas, germinomas, HIV infection, pituitary hemorrhage, drug-induced, combined with neurofibromatosis, as well as diabetes insipidus during pregnancy. The review describes the predictors of the development of diabetes insipidus during surgical interventions, the frequency of development and prognosis in various neurosurgical operations. The article focuses doctors of various specialties on timely diagnosis, prevention and treatment of diabetes insipidus, including its atypical forms.

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The authors declare that there are no conflicts of interest present.