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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rpmj</journal-id><journal-title-group><journal-title xml:lang="ru">Research'n Practical Medicine Journal</journal-title><trans-title-group xml:lang="en"><trans-title>Research and Practical Medicine Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2410-1893</issn><publisher><publisher-name>"QUASAR", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17709/2409-2231-2015-2-2-63-72</article-id><article-id custom-type="elpub" pub-id-type="custom">rpmj-64</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Октреотид в лечении нейроэндокринных опухолей: достигнут ли успех?</article-title><trans-title-group xml:lang="en"><trans-title>Octreotide in the treatment of neuroendocrine carcinomas: Is the success achieved?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Моргунов</surname><given-names>Л. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Morgunov</surname><given-names>L. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">morgunov.l.y@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «МГМСУ имени А.И. Евдокимова» МЗ РФ &#13;
 127473, Российская Федерация, Москва, ул. Делегатская, д.20, стр.1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University of Medicine and Dentistry named after A.I. Evdokimov &#13;
 Ulitsa  Delegatskaya, 20/1, Moskva, 127473, Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>11</day><month>06</month><year>2015</year></pub-date><volume>2</volume><issue>2</issue><fpage>63</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Моргунов Л.Ю., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Моргунов Л.Ю.</copyright-holder><copyright-holder xml:lang="en">Morgunov L.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpmj.ru/rpmj/article/view/64">https://www.rpmj.ru/rpmj/article/view/64</self-uri><abstract><p>Диагностика и лечение функционирующих и нефункционирующих нейроэндокринных опухолей представляет собой сложную задачу. Единственным радикальным методом лечения этих новообразований остается хирургический, но опухоли нередко диагностируются уже на стадии метастазирования, когда возможна лишь паллиативная тактика. Октреотид у пациентов с нейроэндокринными опухолями остается препаратом с доказанной эффективностью, способным подавлять клиническую симптоматику карциноидного синдрома и обладающий антипролиферативной активностью, что позволяет улучшить качество жизни и увеличить выживаемость.</p></abstract><trans-abstract xml:lang="en"><p>Diagnosis and treatment of functioning and non-functioning neuroendocrine tumors is a challenging task. Surgeru remains the only radical method of treatment of these tumors, but tumors often are diagnosed at the stage of metastasis, when only palliative treatment is possible. Octreotide in patients with neuroendocrine tumors remains a drug with proven efficacy that can suppress the clinical symptoms of carcinoid syndrome and has antiproliferative activity, which can improve the quality of life and prolong survival.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>октреотид</kwd><kwd>аналоги соматостатина</kwd><kwd>нейроэндокринные опухоли</kwd><kwd>карциноидный синдром</kwd></kwd-group><kwd-group xml:lang="en"><kwd>octreotide</kwd><kwd>somatostatin analogues</kwd><kwd>neuroendocrine carcinomas</kwd><kwd>carinoid    syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kaltsas G.A., Besser G.M., Grossman A.B. The Diagnosis and medical management of advanced neuroendocrine tumors. Endocr Rev. 2004; 25(3): 458-511.</mixed-citation><mixed-citation xml:lang="en">Kaltsas G.A., Besser G.M., Grossman A.B. 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