rpmjResearch'n Practical Medicine JournalResearch and Practical Medicine Journal2410-1893"QUASAR", LLC10.17709/2410-1893-2021-8-2-11rpmj-728Research ArticleОбзорReviewВыживаемость больных билатеральным почечно-клеточным раком после нефросохраняющей операцииSurvival of patients with bilateral renal cell cancer after nephro-preserving surgeryhttps://orcid.org/0000-0002-1152-0058АшыроваФ. С.AshyrovaF. S.

Ашырова Фидан Самировна – аспирант кафедры онкологии, радиотерапии и пластической хирургии ФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет), 119991, г. Москва, ул. Трубецкая, д. 8, стр. 2; врач-онколог отделения онкоурологии МНИОИ им. П. А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России, 119991, г. Москва, ул. Трубецкая, д. 8, стр. 2, SPIN: 5601-7310, AuthorID: 1070852

Fidan S. Ashyrova – postgraduate student of the department of oncology, radiotherapy and plastic surgery I. M. Sechenov First Moscow State Medical University (8/2 Trubetskaya str., Moscow 119991); the doctor-oncologist at the department of oncourology P. A. Hertsen Moscow Oncology Research Institute - Branch of the National Medical Research Radiological Centre (3 2nd Botkinskiy travel, Moscow 125284), SPIN: 5601-7310, AuthorID: 1070852

fidan_samirovna@bk.ruhttps://orcid.org/0000-0002-2209-3020КалпинскийА. С.KalpinskiyA. S.

Калпинский Алексей Сергеевич – к.м.н., старший научный сотрудник, врач-уролог отдела опухолей репродуктивных и мочевыводящих органов, SPIN: 7253-9356, AuthorID: 655842, ResearcherID: E-9698-2014, Scopus Author ID: 57192806201

125284, Российская Федерация, г. Москва, 2-й Боткинский проезд, д. 3

Aleksey S. Kalpinskiy – Cand. Sci. (Med.), senior researcher, urologist, department of tumors of the reproductive and urinary organs, SPIN: 7253-9356, AuthorID: 655842, ResearcherID: E-9698-2014, Scopus Author ID: 57192806201

3 2nd Botkinskiy travel, Moscow 125284

https://orcid.org/0000-0001-5597-9533ВоробьевН. В.VorobyevN. V.

Воробьев Николай Владимирович – к.м.н., заведующий отделением онкоурологии МНИОИ им. П. А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России (125284, Российская Федерация, г. Москва, 2-й Боткинский проезд, д. 3); доцент кафедры онкологии, радиотерапии и пластической хирургии ФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет), 119991, г. Москва, ул. Трубецкая, д. 8, стр. 2, SPIN: 3426-9843, AuthorID: 195018

Nikolay V. Vorobyev – Cand. Sci. (Med.), head of the department of oncourology P. A. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre (3 2nd Botkinskiy travel, Moscow 125284); urologist, associate professor of the department of oncology, radiotherapy and plastic surgery I. M. Sechenov First Moscow State Medical  University (8/2 Trubetskaya str., Moscow 119991), SPIN: 3426-9843, AuthorID: 195018

https://orcid.org/0000-0001-8784-8415КапринА. Д.KaprinA. D.

Каприн Андрей Дмитриевич – академик РАН, д.м.н., профессор, заслуженный врач РФ, член-корр. РАО, генеральный директор ФГБУ «НМИЦ радиологии» Минздрава России (249036, г. Обнинск, ул. Королева, д. 4); директор МНИОИ им. П. А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России (125284, Российская Федерация, г. Москва, 2-й Боткинский проезд, д. 3); заведующий кафедрой урологии и оперативной нефрологии с курсом онкоурологии медицинского факультета ФГАОУ ВО «Российский университет дружбы народов» (117198, Российская Федерация, г. Москва, ул. Миклухо-Маклая, д. 6); главный уролог АН РФ (г. Москва), SPIN: 1759-8101, AuthorID: 96775, ResearcherID: K-1445-2014, Scopus Author ID: 6602709853

Andrey D. Kaprin – academician of Russian Academy of Sciences, Dr. Sci. (Med.), professor, honored doctor of the Russian Federation, corr. member of the RAE, general director National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (4 Koroleva str., Obninsk 249036); director at the P. A. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre (3 2nd Botkinskiy travel, Moscow 125284); head of the department of urology and operative Nephrology with the course of oncourology of the faculty of medicine Peoples Friendship University of Russia (6 Miklukho-Maklaya str., Moscow 117198), SPIN: 1759-8101, AuthorID: 96775, ResearcherID: K-1445-2014, Scopus Author ID: 6602709853

МНИОИ им. П. А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России; ФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет)РоссияP. A. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre; I. M. Sechenov First Moscow State Medical UniversityRussian FederationМНИОИ им. П. А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава РоссииРоссияP. A. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological CentreRussian FederationФГБУ «НМИЦ радиологии» Минздрава России; МНИОИ им. П. А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России; ФГАОУ ВО «Российский университет дружбы народов»РоссияNational Medical Research Radiological Centre of the Ministry of Health of the Russian Federation; P. A. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre; Peoples Friendship University of Russia (RUDN University)Russian Federation20212306202182124132Copyright © Ашырова Ф.С., Калпинский А.С., Воробьев Н.В., Каприн А.Д., 20212021Ашырова Ф.С., Калпинский А.С., Воробьев Н.В., Каприн А.Д.Ashyrova F.S., Kalpinskiy A.S., Vorobyev N.V., Kaprin A.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rpmj.ru/rpmj/article/view/728

Систематический обзор с целью оценки результатов выживаемости больных билатеральным почечно-клеточным раком, подвергшихся нефросохраняющей операции. Пациенты с билатеральным опухолевым поражением почек представляют собой редкую субпопуляцию, насчитывающую, по данным разных авторов, от 2 до 6 % из общей группы ПКР. Несмотря на рост числа случаев билатерального ПКР, количество работ, посвященных изучению особенностей хирургического вмешательства, факторов прогноза, результатов лечения и выживаемости данного контингента пациентов, ограничено, и ряд важных вопросов, касающихся этой проблемы, остается нерешенным. В настоящее время единственным эффективным методом лечения билатерального рака почек является нефросохраняющая операция в объеме двусторонней резекции почек / нефрэктомии с резекцией контралатеральной почки при синхронном поражении или резекции единственной почки при метахронном поражении, которая позволяет избежать или снизить риск почечной недостаточности и ее последствий после операции.

This article presents a systematic literature review to assess the survival outcomes of patients with bilateral renal cell carcinoma who underwent nephro-preserving surgery. Patients with bilateral renal neoplastic lesions represent a rare subpopulation, numbering, according to different authors, from 2 to 6 % of the total RCC group. Despite the increase in the number of cases of bilateral RCC, the number of works devoted to the study of the features of surgical intervention, prognosis factors, treatment outcomes and survival of this cohort of patients is limited, and a number of important questions regarding this problem remain unresolved. Currently, the only effective method of treating bilateral renal cancer is nephro-preserving surgery in the volume of bilateral renal resection / nephrectomy with resection of the contralateral kidney in case of synchronous lesion or resection of a single kidney in case of metachronous lesion. This strategy avoids or reduces the risk of developing renal failure and its consequences after surgery. Conclusion. Nephro-preserving surgery for bilateral renal cell carcinoma is the only effective method to achieve satisfactory oncological results with a low incidence of complications.

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The authors declare that there are no conflicts of interest present.