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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rpmj</journal-id><journal-title-group><journal-title xml:lang="ru">Research'n Practical Medicine Journal</journal-title><trans-title-group xml:lang="en"><trans-title>Research and Practical Medicine Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2410-1893</issn><publisher><publisher-name>"QUASAR", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17709/2410-1893-2022-9-1-6</article-id><article-id custom-type="elpub" pub-id-type="custom">rpmj-751</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные статьи. Лучевая диагностика, лучевая терапия</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Articles. Radiodiagnosis, Radiotherapy</subject></subj-group></article-categories><title-group><article-title>Роль мультиспиральной компьютерной томографии в выявлении и оценке глубины инвазии рака пищеводно-желудочного перехода</article-title><trans-title-group xml:lang="en"><trans-title>The role of multispiral computed tomography in detecting and the assessment of the degree of damage of esophago-gastric junction cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3627-7971</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Диомидова</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Diomidova</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Диомидова Валентина Николаевна – д.м.н., профессор, заведующая кафедрой пропедевтики внутренних болезней с курсом лучевой диагностики, SPIN: 7628-8435, AuthorID: 512571, ResearcherID: E-4076-2018, Scopus Author ID: 56195523600</p><p>428015, Российская Федерация, г. Чебоксары, Московский пр-т, д. 15</p></bio><bio xml:lang="en"><p>Valentina N. Diomidova – Dr. Sci. (Med.), professor, head of internal medicine department with a course of radiation diagnostics, SPIN: 7628-8435, AuthorID: 512571, ResearcherID: E-4076-2018, Scopus Author ID: 56195523600</p><p>15 Moskovsky Ave., Cheboksary 428015, Russian Federation</p></bio><email xlink:type="simple">diomidovavn@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дмитриева</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Dmitrieva</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитриева Анастасия Николаевна – врач рентгенолог отделения рентгенодиагностики АУ «Республиканский клинический онкологический диспансер» Министерства здравоохранения Чувашской Республики; аспирантка кафедры акушерства и гинекологии ФГБОУ ВО «Чувашский государственный университет им. И. Н. Ульянова», SPIN: 3470-8585, AuthorID: 1072559</p><p>г. Чебоксары</p></bio><bio xml:lang="en"><p>Anastasia N. Dmitrieva – radiologist at the x-ray diagnostics Department, Republican Clinical Oncological Dispensary; PhD student of the Department of obstetrics and gynecology, Chuvash State University named after I. N. Ulyanov, SPIN: 3470-8585, AuthorID: 1072559</p><p>Cheboksary</p></bio><email xlink:type="simple">nastya-himera@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Чувашский государственный университет им. И.Н.Ульянова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chuvash State University named after I. N. Ulyanov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Чувашский государственный университет им. И. Н. Ульянова; Республиканский клинический онкологический диспансер</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chuvash State University named after I. N. Ulyanov; Republican Clinical Oncological Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>18</day><month>02</month><year>2022</year></pub-date><volume>9</volume><issue>1</issue><fpage>65</fpage><lpage>76</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Диомидова В.Н., Дмитриева А.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Диомидова В.Н., Дмитриева А.Н.</copyright-holder><copyright-holder xml:lang="en">Diomidova V.N., Dmitrieva A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpmj.ru/rpmj/article/view/751">https://www.rpmj.ru/rpmj/article/view/751</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Изучить возможности мультиспиральной компьютерной томографии (МСКТ) с внутривенным болюсным контрастированием в выявлении и предоперационном стадировании рака пищеводно-желудочного перехода с целью улучшения дооперационной диагностики данной патологии.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проанализированы результаты мультиспиральной компьютерной томографии пациентов с раком пищеводно-желудочного перехода (n1 = 76), эзофагитом (n2 = 27) и контрольной группы (n3 = 30). Всем пациентам была проведена МСКТ на аппаратах Light Speed VEX Plus и Light Speed RT 16 («GE», США). Результаты МСКТ сопоставлены с морфологическими данными, полученными после гистоморфологического исследования послеоперационного и эндоскопического материалов.</p></sec><sec><title>Результаты</title><p>Результаты. Выявлены характерные МСКТ-признаки стенки пищеводно-желудочного перехода у здоровых лиц, при эзофагите и раке. Толщина стенки пищеводно-желудочного перехода в норме, при эзофагите и раке составила: 5,4 ± 1,01 мм, 10,36 ± 1,85 мм, 22,53 ± 8,19 мм (p &lt; 0,001). Наружный диаметр абдоминального отдела пищевода в норме 14,2 ± 1,68 мм, при эзофагите 17,96 ± 3,7 мм, при раке 27,9 ± 9,48 мм (p &lt; 0,001). Основными статистически значимыми (p &lt; 0,001) качественными признаками рака пищеводно-желудочного перехода были: отсутствие визуализации нормальной структуры слизистой в зоне поражения (96,8 %), бугристые проксимальные и дистальные границы утолщенной стенки (75,2 %), асимметричное утолщение стенки (70,4 %), неровный наружный контур стенки (58,4 %), наличие чашеобразного супрастенотического расширения просвета пищевода (45,6 %). Чувствительность МСКТ зависела от глубины инвазии опухоли и составила при стадии Т1 – 66,7 %, Т2 – 76,5 %, Т3 – 77,8 %,, Т4а – 86,2 %, Т4б – 100,0 %; в целом диагностическая точность метода в Т-стадировании рака пищеводно-желудочного перехода (РПЖП) составила 81,6 %.</p></sec><sec><title>Заключение</title><p>Заключение. Результаты работы показали, что включение МСКТ с внутривенным болюсным контрастированием в алгоритм исследования пациентов с подозрением на опухолевую патологию пищеводно-желудочного перехода позволит улучшить диагностику РПЖП.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose of the study</title><p>Purpose of the study. To find out the abilities of multispiral computed tomography (MSCT) using intravenous bolus injection in detecting and preoperative esophago-gastric junction cancer staging in order to improve preoperative diagnosis of this pathological condition.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The patients, diagnosed esophago-gastric junction cancer (n1 = 76), esophagus (n2 = 27) and medically fit people’s (n3 = 30) findings of investigating have been analyzed. All patients went through computed tomography on Light Speed VEX Plus and Light Speed RT 16 ("GE", The USA). The findings of MSCT have been compared with anatomical data, which were got after histomorphologic study of post-operation and endoscopic recruitment material.</p></sec><sec><title>Results</title><p>Results. Characteristic MSCT signs of the wall of the esophageal-gastric junction (EGJ) were revealed in healthy individuals, with esophagitis and cancer. The thickness of esophagus paries in normal conditions and in case of esophagitis and EGJ cancer is: 5.4 ± 1.01 mm, 10.36 ± 1.85 mm, 22.53 ± 8.19 mm (p &lt; 0.001). The external diameter of the abdominal part of esophagus in the normal condition is 14.2 ± 1.68 mm, in case of esophagitis is 17.96 ± 3.7 mm, EGJ cancer is 27.9 ± 9.48 mm (p &lt; 0.001). The main statistically significant (p &lt; 0.001) qualitative character of esophago-gastric junction canser were: non-visualization of mucic in afflicted areas (96.8 %), bosselated upper and lower contours of narrowing (75.2 %), dissymmetric parries pachymenia (70.4 %), blunt-edged outer contours (58.4 %), cotyloid suprastenotic esophageal distensibility (45.6 %). The delicacy depended on the degree of damage delicacy and was at the stage Т1 – 66.7 %, Т2 – 76.5 %, Т3 – 77.8 %, Т4а – 86.2 %, Т4b –100.0 %, in general, diagnostic accuracy of the method in EGJ cancer Т-staging was 81.6 %.</p></sec><sec><title>Conclusion</title><p>Conclusion. The results of the work showed that the inclusion of MSCT with intravenous bolus contrast in the algorithm of the study of patients with suspected tumor pathology of the EGJ will improve the diagnosis of cancer of the EGJ.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>рак</kwd><kwd>желудок</kwd><kwd>пищеводно-желудочный переход</kwd><kwd>МСКТ</kwd><kwd>стадирование</kwd><kwd>болюсное контрастирование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cancer</kwd><kwd>stomach</kwd><kwd>esophago-gastric junction</kwd><kwd>MSCT</kwd><kwd>staging</kwd><kwd>bolus injection</kwd></kwd-group><funding-group><funding-statement xml:lang="en">no</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. 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