BONE SEVERE FORM OF HYPERPARATHYROIDISM IN A PATIENT WITH ADENOMA OF PARATHYROID GLAND
K. M. Petrosyan,
N. V. Severskaya,
D. N. Derbugov,
A. A. Kuril'chik,
N. V. Zhelonkina,
A. V. Dement'ev,
E. I. Kupriyanova,
G. A. Davydov,
A. D. Kaprin,
V. N. Galkin,
S. A. Ivanov https://doi.org/10.17709/2409-2231-2018-5-1-11
Abstract
Hyperparathyroidism is one of the most common endocrinopathies. This disease leads to a violation of phosphorus-calcium metabolism and the washing out of calcium from bone tissue. Breach of the skeleton’s structure in hyperparathyroidism is often mistaken for metastatic bone damage, which leads to incorrect treatment tactics. In this work we present the clinical observation of a patient with an adenoma of the parathyroid gland and a severe bone form of hyperparathyroidism. Multiple lesions of bones with destruction of the cortical layer and the presence of the softtissue component were initially regarded as metastases in the bone. However, the morphological pattern of bone foci, as well as an elevated level of calcium and parathyroid hormone, made it possible to diagnose the bony form of hyperparathyroidism. The search for the cause of hyperparathyroidism revealed a tumor in the projection of the right lower parathyroid gland. Surgical removal of parathyroid adenoma led to the normalization of the level of calcium and parathyroid hormone. The article presents data of laboratory-instrumental methods of research and the results of surgical treatment of a patient.
About the Authors
K. M. Petrosyan
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Karina M. Petrosyan - junior researcher of the department of radionuclide diagnostics.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036
N. V. Severskaya
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Natal’ya V. Severskaya - MD, PhD, endocrinologist of the highest category, head of the department «In-vitro» radionuclide diagnostics.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036
D. N. Derbugov
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Dmitrii N. Derbugov - oncologist of the department of radiosurgical treatment with closed radionuclides.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036
A. A. Kuril'chik
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Aleksandr A. Kuril’chik - MD, PhD, leading research offi cer, radiologist, oncologist of the radiological department with a group of radiation and surgical treatment of bone tumors.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036
N. V. Zhelonkina
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Natal’ya V. Zhelonkina - MD, PhD, senior researcher of the department of ultrasound diagnostics and minimally invasive technologies.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036
A. V. Dement'ev
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Andrey V. Dement’ev - radiologist, department of computed tomography.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036
E. I. Kupriyanova
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Ekaterina I. Kupriyanova - pathologist, doctor of pathoanatomical department.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036
G. A. Davydov
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
German A. Davydov - MD, PhD, head of the department of radionuclide diagnosis.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036A. D. Kaprin
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Andrey D. Kaprin - Academician of RAS, MD, PhD, DSc, Prof.; Corr. member of the RAE; Honored Physician of the RF; General Director of NMRRC, Head of Department of Urology with Course of Urological Oncology, Faculty for Postgraduate Training, PFUR.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036
V. N. Galkin
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Vsevolod N. Galkin - MD, PhD, DSc, head.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036
S. A. Ivanov
A. Tsyb Medical Radiological Research Centre – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Sergey A. Ivanov - MD, PhD, DSc, deputy general director for work with branches.
10 Marshala Zhukova str., Kaluga Region, Obninsk, 249036
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Review
For citations:
Petrosyan K.M., Severskaya N.V., Derbugov D.N., Kuril'chik A.A., Zhelonkina N.V., Dement'ev A.V., Kupriyanova E.I., Davydov G.A., Kaprin A.D., Galkin V.N., Ivanov S.A. BONE SEVERE FORM OF HYPERPARATHYROIDISM IN A PATIENT WITH ADENOMA OF PARATHYROID GLAND. Research and Practical Medicine Journal. 2018;5(1):96-105. (In Russ.) https://doi.org/10.17709/2409-2231-2018-5-1-11
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