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Erectile dysfunction is no longer a psychosocial problem. Nowadays, it is a marker specific for the initial stages of cardiovascular diseases. Рlatelet-rich plasma (PRP) is a new and promising method, which totally deserves to be noted by specialists. To review currently existing pre-clinical and clinical studies concerning application of PRP in erectile dysfunction published in international sources such as PubMed, Cochrane Library, The current data of preclinical and clinical studies determine the absence of PRP side effects and the effectiveness for ED treatment. PRP-therapy is a pathogenetically substantiated method of treating erectile dysfunction. The therapy is designed for repair and regeneration of endothelium, smooth muscle cells, and connective tissue. However, large, placebo-controlled, multicenter studies are needed to creation a systematic review and meta-analysis.

About the Authors

A. D. Kaprin
National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation; Medical Institute of Peoples' Friendship University of Russia (RUDN University)
Russian Federation
academician of RAS, MD, PhD, professor, head of the department of urology and operative nephrology with oncourology course of the Medical Institute of Peoples’ Friendship University (RUDN University), General Director of National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation

A. A. Kostin
National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation; Peoples' Friendship University of Russia (RUDN University)
Russian Federation
MD, PhD, DSc, professor, head of the department of urology with oncology, radiology and andrology courses of the Continuing Medical Education of Peoples’ Friendship University (RUDN University), Deputy Director of National Medical Radiology Research Centre of the Ministry of Health of the Russian Federation

M. V. Epifanova
Medical Institute of Peoples' Friendship University of Russia (RUDN University) Peoples' Friendship University of Russia (RUDN University)
Russian Federation
MD, PhD, associate professor at the department of urology and operative nephrology with oncourology course of the Medical Institute of Peoples’ Friendship University of Russia (RUDN University), associate professor at the department of urology with oncology, radiology and andrology courses of the Continuing Medical Education of Peoples’ Friendship University (RUDN University)

M. E. Chalyy
Medical Research and Education Center of Lomonosov Moscow State University
Russian Federation
MD, PhD, DSc, professor, leading researcher

E. V. Gameeva
P. Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
Russian Federation
MD, PhD, deputy director for medical work

S. A. Artemenko
I.M.Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
sixth year student, International School «Medicine of the Future»


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For citation:

Kaprin A.D., Kostin A.A., Epifanova M.V., Chalyy M.E., Gameeva E.V., Artemenko S.A. PLATELET-RICH PLASMA THERAPY FOR ERECTILE DYSFUNCTION: A REVIEW OF PRECLINICAL AND CLINICAL STUDIES. Research and Practical Medicine Journal. 2019;6(3):74-86. (In Russ.)

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ISSN 2409-2231 (Print)
ISSN 2410-1893 (Online)