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Surgical treatment of patients with renal cell cancer complicated by specific (tumor) and non-specific thrombosis of the inferior Vena cava

https://doi.org/10.17709/2409-2231-2020-7-3-9

Abstract

Among malignant neoplasms, kidney cancer occupies one of the first places in terms of the growth rate of incidence in Russia. Despite the possibilities of modern diagnostic research methods, the number of patients with common forms of the disease does not decrease. In 5–10% of cases, renal cell carcinoma is complicated by the formation of a tumor clot in the inferior Vena cava (VCI), which requires volume surgery — nephrectomy with thrombectomy, which is the only effective treatment option for this group of patients. Previously, the results of treatment of locally advanced kidney cancer were unsatisfactory due to the high incidence of complications and mortality after extended surgical interventions. However, improving the operation technique requires a re-evaluation of previous representations. Performing a nephrectomy with a VCI thrombectomy is not an easy task and is often associated not only with technical difficulties due to the need for mobilization, control and resection of the inferior Vena cava, but also with the risk of intra — and postoperative complications. The most difficult task is the choice of surgical tactics for descending non-tumor hemorrhagic thrombosis. As a result of long-term tumor obstruction, organized blood clots that are soldered to the intima of the vessel often spread to the common iliac veins and, as a rule, are technically impossible to remove. If the VCI is preserved, a residual hemorrhagic blood clot in the area of its confluence is a potential source of pulmonary embolism (PE), for the prevention of which mechanical plication is used. This maneuver does not lead to the development of clinically significant chronic venous insufficiency of the lower extremities (CVI NC), postoperative VCI or PE thrombosis. Despite the technical complexity of the operation and the difficult course of the postoperative period, surgical treatment of renal cell cancer complicated by tumor thrombosis is certainly justified. This article presents a clinical case of surgical treatment of a patient with renal cell cancer complicated by massive specific (tumor) and non-specific thrombosis in the presence of reduced parenchymalexcretory function of the contralateral kidney and severe cardiac pathology.
Goal
: to share experience and demonstrate the results of successful surgical treatment of renal cell carcinoma.

About the Authors

N. V. Vorobev
P.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre; I.M.Sechenov First Moscow State Medical University
Russian Federation

Nikolay V. Vorobyev – Cand. Sci. (Med.), head of the department of oncourology; Urologist, associate professor of the department of Oncology, radiotherapy and plastic surgery

3 2nd Botkinskiy travel, Moscow 125284

8/2 Trubetskaya str., Moscow 119991

SPIN: 3426-9843

AuthorID: 195018



F. S. Ashyrova
P.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre
Russian Federation

Fidan S. Ashyrova – the doctor-oncologist of the department of oncourology

3 2nd Botkinskiy travel, Moscow 125284

SPIN: 5601-7310

AuthorID: 1070852



M. P. Golovashchenko
P.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre
Russian Federation

Maksim P. Golovashchenko – Cand. Sci. (Med.), oncologist, researcher at the department of oncourology

3 2nd Botkinskiy travel, Moscow 125284

SPIN: 8082-1075

AuthorID: 714890



L. O. Petrov
P.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre; A.F.Tsyb Medical Radiological Research Center – Branch of the National Medical Research Radiological Center
Russian Federation

Leonid O. Petrov – Cand. Sci. (Med.), head of the department of radiation and surgical treatment of abdominal diseases

3 2nd Botkinskiy travel, Moscow 125284

4 Korolev str., Obninsk 249036

SPIN: 4559-3613

AuthorID: 665865



A. D. Kaprin
P.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre; Peoples Friendship University of Russia
Russian Federation

Andrey D. Kaprin – academician of the Russian Academy of Sciences, Dr. Sci. (Med.), general Director; Head of the department of urology with the course of oncourology

3 2nd Botkinskiy travel, Moscow 125284

6 Miklukho-Maklaya str., Moscow 117198

SPIN: 1759-8101

AuthorID: 96775

ResearcherID: K-1445-2014

Scopus Author ID: 6602709853



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Review

For citations:


Vorobev N.V., Ashyrova F.S., Golovashchenko M.P., Petrov L.O., Kaprin A.D. Surgical treatment of patients with renal cell cancer complicated by specific (tumor) and non-specific thrombosis of the inferior Vena cava. Research and Practical Medicine Journal. 2020;7(3):91-98. (In Russ.) https://doi.org/10.17709/2409-2231-2020-7-3-9

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