A METHOD OF PREDICTING BREAST CANCER USING QUESTIONNAIRES
https://doi.org/10.17709/2409-2231-2017-4-1-9
Abstract
Purpose. Simplify and increase the accuracy of the questionnaire method of predicting breast cancer (BC) for subsequent computer processing and Automated dispensary at risk without the doctor.
Materials and methods. The work was based on statistical data obtained by surveying 305 women. The questionnaire included 63 items: 17 open-ended questions, 46 — with a choice of response. It was established multifactor model, the development of which, in addition to the survey data were used materials from the medical histories of patients and respondents data immuno-histochemical studies. Data analysis was performed using Statistica 10.0 and MedCalc 12.7.0 programs.
Results. The ROC analysis was performas and the questionnaire data revealed 8 significant predictors of breast cancer. On their basis we created the formula for calculating the prognostic factor of risk of development of breast cancer with a sensitivity 83,12% and a specificity of 91,43%.
Conclusions. The completed developments allow to create a computer program for automated processing of profiles on the formation of groups at risk of breast cancer and clinical supervision. The introduction of a screening questionnaire over the Internet with subsequent computer processing of the results, without the direct involvement of doctors, will increase the coverage of the female population of the Russian Federation activities related to the prevention of breast cancer. It can free up time for physicians to receive primary patients, as well as improve oncological vigilance of the female population of the Russian Federation.
About the Authors
V. N. Malashenko
Yaroslavl State Medical University
Russian Federation
Russian Federation
MD, professor, Head of the Department of Oncology with Hematology,
5 ul. Revolyutsionnaya Yaroslavl’ 150000
A. V. Sgonnik
Yaroslavl State Medical University
Russian Federation
Russian Federation
student of the 6th course of Medical Faculty,
5 ul. Revolyutsionnaya Yaroslavl’ 150000
References
1. Malignansies in Russia in 2011. Ed by Chissov VI, Starinskii VV, Petrova GV. Мoscow, 2013. Available at: http://www.oncology.ru/service/statistics/malignant_tumors/2011.pdf (In Russian).
2. The state of Russian population cancer care in 2014. Ed by Kaprin AD, Starinskii VV, Petrova GV. Мoscow: P. Hertsen Moscow Oncology Research Institute, 2015.
3. Semiglazov VF, Semiglazov VV. Skrining raka molochnoi zhelezy. Practical Oncology. 2010; 11 (2): 60–65. (In Russian).
4. Autier P, Boniol M, Middleton R, Doré JF, Héry C, Zheng T, et al. Advanced breast cancer incidence following population-based mammographic screening. Ann Oncol. 2011 Aug; 22 (8): 1726–3175. DOI: 10.1093/annonc/mdq633
5. Nederend J, Duijm LE, Voogd AC, Groenewoud JH, Jansen FH, Louwman MW. Trends in incidence and detection of advanced breast cancer at biennial screening mammography in The Netherlands: a population based study. Breast Cancer Res. 2012 Jan 9; 14 (1): R10. DOI: 10.1186/bcr3091
6. Lauby-Secretan B, Scoccianti C, Loomis D, Benbrahim-Tallaa L, Bouvard V, Bianchini F, et al. Breast-cancer screening — viewpoint of the IARC Working Group. N Engl J Med. 2015 Jun 11;372 (24):2353–8. DOI: 10.1056/NEJMsr1504363
7. Erpeldinger S, Fayolle L, Boussageon R, Flori M, Lainé X, Moreau A, et al. Is there excess mortality in women screened with mammography: a meta-analysis of nonbreast cancer mortality. Trials. 2013 Nov 5; 14: 368. DOI: 10.1186/1745–6215–14–368
8. Miller AB, Wall C, Baines CJ, Sun P, To T, Narod SA. Twenty five year follow-up for breast cancer incidence and mortality of the Canadian National Breast Screening Study: randomised screening trial. BMJ. 2014 Feb 11;348: g366. DOI: 10.1136/bmj.g366
9. Pace LE, Keating NL. A systematic assessment of benefits and risks to guide breast cancer screening decisions. JAMA. 2014 Apr 2; 311 (13): 1327–1335. DOI: 10.1001/jama.2014.1398
10. Organizatsiya provedeniya dispanserizatsii i profilakticheskikh meditsinskikh osmotrov vzroslogo naseleniya [Organization of clinical examination and preventive medical examinations of the adult population]. Guidelines. Moscow: National Research Center for Preventive Medicine, 2013. Available at: http://www.rakpobedim.ru/fileadmin/user_upload/pdf/metodrek_po_d.pdf (In Russian).
11. Vilyanskii MP, Uglev NN. Skrining v massovykh profilakticheskikh osmotrakh: avtomatizirovannaya sistema [Screening in mass prophylactic examinations: an automated system]. Мoscow, 1987, 160 p. (In Russian).
Review
For citations:
Malashenko V.N., Sgonnik A.V. A METHOD OF PREDICTING BREAST CANCER USING QUESTIONNAIRES. Research and Practical Medicine Journal. 2017;4(1):68-73. (In Russ.) https://doi.org/10.17709/2409-2231-2017-4-1-9
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