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POPULATION-BASED ASSESSMENT OF THE RECTAL CANCER STAGE STRUCTURE AND INCIDENCE AFTER IMPLEMENTATION OF THE NATIONAL PROJECT “HEALTH” AND ALL-NATIONAL DISPENSARIZATION IN THE ARKHANGELSK REGION, RUSSIA (THE RESULTS OF THE PRELIMINARY STUDY)

https://doi.org/10.17709/2409-2231-2017-4-3-3

Abstract

Objective. Assessment of the rectal cancer (RC) incidence and stage structure trends in the Arkhangelsk region (AR), Russia before and after implementation of national programs for health system reforming based on population data of the Arkhangelsk Regional Cancer Registry (ARCR) over the period 2000–2015.

Materials and methods. Anonymized data on all cases of RC (C19.0‑C21.0) in the AR in 2000–2015 were extracted from the database of the ARCR. Over the study period, 3721 cases of the RC were selected. Age-standardized (ASR) RC incidence rate was calculated. Population number and its age distribution were taken from the Regional Bureau of Statistics, Arkhangelskstat. Time trends were analyzed using segmented regression.

Results. Over the period, an incidence (ASR) of RC in AR increased from 11.5 to 14.2 per 100000. The incidence rates in the male population were higher than in women: 20.3 vs 12.6 in 2015. The growing trend of male incidence was stable. The ASR of RC incidence in female increased significantly by 4.6% per year in 2011–2015. RC ASRs for both urban and rural populations were growing, 12.3 and 20.4 per 100000 in 2015, respectively. StagesI, II, III and IV were established in 14%, 50%, 9% and 21% of cases, however, the stage I in urban residents was detected 4% more often. The proportion of stage I non-significantly varied from 10.6% to 13.3% in 2000–2015. After the introduction of the National Project “Health”, the proportion of the stage IV non-significantly decreased by 5.4% per year, same after the introduction of the All-national Dispensarization it non-significantly increased by 5.4% per year.

Conclusion. Implementation of national programs for health system reforming didn’t provide significant improvement in earlier detection of RC. Introduction of national screening programs is necessary. A higher incidence rates among males and rural population require detailed analysis. 

About the Authors

D. M. Dubovichenko
Arkhangelsk Clinical Oncology Hospital; Northern State Medical University
Russian Federation

oncologist of chemotherapy day hospital cabinet, 145/1 Obvodny canal Pr., Arkhangelsk, 163045;

postgraduate student of the Department of Radiation Diagnosis, Radiotherapy and Oncology, 51 Troitsky Pr., Arkhangelsk, 163000



M. Y. Valkov
Arkhangelsk Clinical Oncology Hospital; Northern State Medical University
Russian Federation

MD, professor, head of the Department of Radiation Diagnosis, Radiotherapy and Oncology, 145/1 Obvodny canal Pr., Arkhangelsk, 163045

physician of the Radiotherapy Department, 51 Troitsky Pr., Arkhangelsk, 163000



A. A. Karpunov
Northern State Medical University
Russian Federation

PhD, acting head of Department of Clinical Oncology,

51 Troitsky Pr., Arkhangelsk, 163000



A. Yu. Pankrat'eva
Arkhangelsk Clinical Oncology Hospital
Russian Federation

chief physician,

145/1 Obvodny canal Pr., Arkhangelsk, 163045



References

1. Haggar FA, Boushey RP. Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors. Clinics in Colon and Rectal Surgery. 2009; 22 (4): 191–197. DOI: 10.1055/s‑0029–1242458

2. GLOBOCAN 2012: estimated cancer incidence, mortality and prevalence worldwide in 2012 [accessed 15.04.2017]. Available at: http://globocan.iarc.fr/Default.aspx

3. Amersi F, Agustin M, Ko CY. Colorectal Cancer: Epidemiology, Risk Factors, and Health Services. Clinics in Colon and Rectal Surgery. 2005; 18 (3):133–140. DOI: 10.1055/s‑2005–916274

4. Fung TT, Brown LS. Dietary Patterns and the Risk of Colorectal Cancer. Current nutrition reports. 2013; 2 (1): 48–55. DOI:10.1007/s13668–012–0031–1

5. Lebedeva LN, Valkov MYu, Asakhin SM, Krasilnikov AV. Dynamics of the incidence and mortality of colon cancer in 2000–2010 in Arkhangelsk region (population study). Human Ecology. 2014; 9:18–23. (In Russian).

6. Lebedeva LN, Val’kov MYu, Asakhin SM, Krasil’nikov AV. The population characteristics of colon cancer in the Nord-West Russia: data of the regional cancer registry. Vestnik Rossiiskogo nauchnogo tsentra rentgenoradiologii Minzdrava Rossii. 2014; 1: 6. (In Russian).

7. Janout V, Kollárová H. Epidemiology of colorectal cancer. Biomed Pap Med FacUnivPalacku Olomouc Czech Repub. 2009; 145: 5–10.

8. Boyle P, Ferlay J. Mortality and survival in breast and colorectal cancer. Nat Clin Pract Oncol. 2005; 2 (9): 424–425. DOI: 10.1038/ncponc0288

9. Kaprin AD, Starinskii VV, Petrova GV. Malignant neoplasms in Russia in 2015. Moscow: P. Hertsen Moscow Oncology Research Institute — Branch of the National Medical Research Radiological Centre, 2017. Available at: http://www.oncology. ru/service/statistics/malignant_tumors/2015.pdf [accessed 15.04.2017]. (In Russian).

10. Tatyana Golikova: Health should be a priority in the system of national values. Available at: http://www.medvestnik.ru/archive/tatyana_golikova_zdorove_dolzhno_stat_prioritetom_v_sisteme_socialnyh_cennostey.html [accessed 15.04.2017]. (In Russian).

11. Vaktskjold A, Lebedintseva JA, Korotov DS. Cancer incidence in Arkhangelskaja Oblast in Northwestern Russia. The Arkhangelsk Cancer Registry. BMC Cancer. 2005; 5: 82. DOI: 10.1186/1471–2407–5-82

12. Allemani C, Weir HK, Carreira H, Harewood R, Spika D, Wang XS, et al. Global surveillance of cancer survival 1995–2009: analysis of individual data for 25 676 887 patients from 279 population-based registries in 67 countries (CONCORD‑2). Lancet (London, England). 2015; 385 (9972): 977–1010. DOI: 10.1016/S0140–6736 (14)62038–9

13. Geiger TM, Ricciardi R. Screening Options and Recommendations for Colorectal Cancer. Clinics in Colon and Rectal Surgery. 2009; 22 (4): 209–217. DOI: 10.1055/s‑0029–1242460

14. Doubeni CA, Weinmann S, Adams K. Screening colonoscopy and risk of incident late-stage colorectal cancer diagnosis in average-risk adults: a nested case-control study. Ann Intern Med. 2013 Mar 5;158 (5 Pt 1):312–20. DOI: 10.7326/0003–4819–158–5-201303050–00003

15. Pathy S, Lambert R, Sauvaget C, Sankaranarayanan R. The incidence and survival rates of colorectal cancer in India remain low compared with rising rates in East Asia. Dis Colon Rectum. 2012; 55 (8): 900–6. DOI: 10.1097/DCR.0b013e31825afc4e

16. Kinney AY, Harrell J, Slattery M, Martin C, Sandler RS. Rural-urban differencesin colon cancer risk in blacks and whites: the North Carolina Colon Cancer Study. J Rural Health. 2006; 22 (2): 124–30

17. Chow CJ, Al-Refaie WB, Abraham A. Does Patient Rurality Predict Quality Colon Cancer Care? A Population Based Study. Diseases of the colon and rectum. 2015; 58 (4): 415–422. DOI: 10.1097/DCR.0000000000000173

18. Bretthauer M. Evidence for colorectal cancer screening. Best Practice & Research Clinical Gastroenterology. 2010; 24: 417–425. DOI: 10.1016/j.bpg.2010.06.005

19. El Zoghbi M, Cummings LC. New era of colorectal cancer screening. World J Gastrointest Endosc. 2016 Mar 10;8 (5):252–8. DOI: 10.4253/wjge.v8.i5.252


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For citations:


Dubovichenko D.M., Valkov M.Y., Karpunov A.A., Pankrat'eva A.Yu. POPULATION-BASED ASSESSMENT OF THE RECTAL CANCER STAGE STRUCTURE AND INCIDENCE AFTER IMPLEMENTATION OF THE NATIONAL PROJECT “HEALTH” AND ALL-NATIONAL DISPENSARIZATION IN THE ARKHANGELSK REGION, RUSSIA (THE RESULTS OF THE PRELIMINARY STUDY). Research and Practical Medicine Journal. 2017;4(3):23-32. (In Russ.) https://doi.org/10.17709/2409-2231-2017-4-3-3

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ISSN 2410-1893 (Online)