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Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical cases

https://doi.org/10.17709/2409-2231-2020-7-2-14

Abstract

Currently the main way of curable treatment of hepatocellular carcinomas (HCC)* is a liver resection. Candidates for surgery are patient with good score of liver function (Child-Pugh A group), without destruction of great vessels and distant metastases. Hemihepatectomy is associated with a high risk of postoperative liver failure (including portal hypertension, cirrhosis, portal vein thrombosis). This reason leads to premature failure of the operation. According to current clinical guidelines, system therapy is more suitable, despite of the lack of reliable data on its effectiveness in such clinical situations. The presented cases may support the selection of advanced hemihepatectomy as a treatment for hepatocellular cancer C stage BCLC classification.

About the Authors

D. V. Sidorov
P.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre
Russian Federation

Dmitrii V. Sidorov – Dr. Sci. (Med.), head of the department of abdominal oncology

3 2nd Botkinskiy travel, Moscow 125284

SPIN: 1670-3690

AuthorID: 642999 



M. V. Lozhkin
P.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre
Russian Federation

Mikhail V. Lozhkin – Cand. Sci. (Med.), leading researcher of the department of abdominal oncology

3 2nd Botkinskiy travel, Moscow 125284

SPIN: 4982-5909

AuthorID: 652950 



L. O. Petrov
A.F.Tsyb Medical Radiological Research Center – Branch of the National Medical Research Radiological Center
Russian Federation

Leonid O. Petrov – Cand. Sci. (Med.), head of department of radiation and surgical treatment of abdominal diseases

4 Korolev str., Obninsk 249036

SPIN: 4559-3613

AuthorID: 665865




A. G. Isaeva
A.F.Tsyb Medical Radiological Research Center – Branch of the National Medical Research Radiological Center
Russian Federation

Aisha G. Isaeva – assistant research fellow

4 Korolev str., Obninsk 249036

SPIN: 7121-6391

AuthorID: 945036




M. S. Gusakova
P.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre
Russian Federation

Mariya S. Gusakova – resident physician

3 2nd Botkinskiy travel, Moscow 125284



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For citations:


Sidorov D.V., Lozhkin M.V., Petrov L.O., Isaeva A.G., Gusakova M.S. Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical cases. Research and Practical Medicine Journal. 2020;7(2):154-163. (In Russ.) https://doi.org/10.17709/2409-2231-2020-7-2-14

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ISSN 2410-1893 (Online)