Acute mesenteric ischemia: experience in the treatment of patients at a multidisciplinary hospital
https://doi.org/10.17709/2410-1893-2026-13-3-6
Abstract
Acute mesenteric ischemia is a group of conditions characterized by an acute impairment of intestinal blood supply, resulting in critical ischemia and necrosis of the affected bowel segments.
Purpose of the study. To analyze the diagnostic and treatment outcomes of patients with acute mesenteric ischemia in a multidisciplinary hospital and to evaluate the outcomes of surgical treatment strategies incorporating endovascular techniques.
Patients and methods. A retrospective analysis was performed of the diagnostic and treatment outcomes of 73 patients admitted to a multidisciplinary hospital between 2021 and 2023. The study included 50 (68.49 %) women and 23 (31.51 %) men. The mean age of the patients was 75.3 ± 9.05 years. The time from the onset of the first symptoms to transport by ambulance and hospital admission was up to 6 h in 23 patients (31.5 %), 6–24 h in 20 patients (27.4 %), and more than 24 h in 30 patients (41.1 %). Depending on the diagnostic and treatment strategy used, the patients were divided into five groups.
Results. The overall mortality rate in the study cohort was 69.86 %. Mortality rates varied according to the diagnostic and treatment strategy. The lowest mortality rate was observed in the group receiving endovascular treatment alone (44.4 %). Mortality was 54.55 % in the group undergoing combined endovascular and open surgical treatment, 71.4 % in the group undergoing surgical treatment alone, 100 % in the group undergoing combined open vascular and surgical interventions, and 100 % in the group receiving conservative treatment.
Conclusion. Rapid transport of patients with acute mesenteric ischemia to a multidisciplinary hospital and timely CT angiography improve diagnostic accuracy, shorten the time to diagnosis, facilitate the selection of an appropriate treatment strategy, and reduce the risk of adverse outcomes. The use of endovascular techniques to restore mesenteric vessel patency as part of the comprehensive treatment of acute mesenteric ischemia reduces mortality.
About the Authors
V. V. ZeleninRussian Federation
Vyacheslav V. Zelenin – Cand. Sci. (Medicine), Associate Professor, Department of Hospital Surgery with Courses in Traumatology and Military Field Surgery;
Head of the Department of Endovascular Diagnostic and Treatment Methods, Saint Petersburg
I. A. Soloviev
Russian Federation
Ivan A. Soloviev – Dr. Sci. (Medicine), Professor, Department of Hospital Surgery with Courses in Traumatology and Military Field Surgery;
Associate Professor, Department of Naval Surgery;
Deputy Chief Physician for Surgery, Saint Petersburg
A. A. Petrov
Russian Federation
Anton A. Petrov – Resident, Department of Endovascular Diagnostic and Treatment Methods,
Saint Petersburg
D. S. Shcheglov
Russian Federation
Dmitrii S. Shcheglov – Cand. Sci. (Medicine), Physician, Department of Endovascular Diagnostic and Treatment Methods,
Saint Petersburg
O. I. Kudryavcev
Russian Federation
Oleg I. Kudryavcev – Cand. Sci. (Medicine), Physician, Department of Endovascular Diagnostic and Treatment Methods,
Saint Petersburg
V. V. Akhmetov
Russian Federation
Vladimir V. Akhmetov – Cand. Sci. (Medicine), Associate Professor, Department of General and Faculty Surgery,
Petrozavodsk
I. P. Dudanov
Russian Federation
Ivan P. Dudanov – Corresponding Member of the Russian Academy of Sciences, Dr. Sci. (Medicine), Professor, Head of the Department of General and Faculty Surgery, Petrozavodsk;
Professor, Prof. A. A. Rusanov Department of Faculty Surgery;
Surgeon, Department of Vascular Surgery, Saint Petersburg
References
1. Acosta S. Mesenteric ischemia. Curr Opin Crit Care. 2015 Apr;21(2):171–178. https://doi.org/10.1097/mcc.0000000000000189
2. Bala M, Catena F, Kashuk J, De Simone B, Gomes CA, Weber D, Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery. World J Emerg Surg. 2022 Oct 19;17(1):54. https://doi.org/10.1186/s13017-022-00443-x
3. Chang RW, Chang JB, Longo WE. Update in management of mesenteric ischemia. World J Gastroenterol. 2006 May 28;12(20):3243–3247. https://doi.org/10.3748/wjg.v12.i20.3243
4. Horton KM, Fishman EK. Multidetector CT angiography in the diagnosis of mesenteric ischemia. Radiol Clin North Am. 2007 Mar;45(2):275–288. https://doi.org/10.1016/j.rcl.2007.03.010
5. Schoots IG, Koffeman GI, Legemate DA, Levi M, van Gulik TM. Systematic review of survival after acute mesenteric ischaemia according to disease aetiology. Br J Surg. 2004 Jan;91(1):17–27. https://doi.org/10.1002/bjs.4459
6. Beaulieu RJ, Arnaoutakis KD, Abularrage CJ, Efron DT, Schneider E, Black JH 3rd. Comparison of open and endovascular treatment of acute mesenteric ischemia. J Vasc Surg. 2014 Jan;59(1):159–164. https://doi.org/10.1016/j.jvs.2013.06.084
7. Sarac TP. Techniques of endovascular revascularization for acute mesenteric ischemia. New York: Springer; 2015, pp. 241–252.
8. Wan Z, Ignashov AM, Dudanov IP, Khirmanov VN, Doynikov DN, Morozov AN, et al. Repeated operations in patients with unsatisfactory results of celiac artery compression syndrome treatment. Research and Practical Medicine Journal. 2019;6(4):116–126. (In Russ.). https://doi.org/10.17709/2409-2231-2019-6-4-12
9. Dudanov IP, Soloviev IA, Zelenin VV, Khanevich MD, Kudryavtsev OI, Petrov AA. Vascular diseases of the intestine. Acute and chronic mesenteric ischemia. Edited by Dudanov IP, Soloviev IA. Petrozavodsk, 2025, 152 p. (In Russ.).
10. Podoluzhnyi VI, Startsev AB, Radionov IA. Acute mesenterial ischaemia: a contemporary view. Fundamental and Clinical Medicine. 2023;8(1):101–108. (In Russ.). https://doi.org/10.23946/2500-0764-2023-8-1-101-108
11. Acute vascular intestinal diseases in adults. Draft national clinical guidelines. Russian Society of Surgeons. Moscow, 2018. (In Russ.).
12. Naazar AA, Omair A, Chu SH, Keane KG, Weber DG. A Shifting Trend Towards Endovascular Intervention in the Treatment of Acute Mesenteric Ischemia. Cureus. 2021 Oct 6;13(10):e18544. https://doi.org/10.7759/cureus.18544
13. Acosta-Mérida MA, Marchena-Gómez J, Saavedra-Santana P, Silvestre-Rodríguez J, Artiles-Armas M, Callejón-Cara MM. Surgical Outcomes in Acute Mesenteric Ischemia: Has Anything Changed Over the Years? World J Surg. 2020 an;44(1):100–107. https://doi.org/10.1007/s00268-019-05183-9
14. Arthurs ZM, Titus J, Bannazadeh M, Eagleton MJ, Srivastava S, Sarac TP, et al. A comparison of endovascular revascularization with traditional therapy for the treatment of acute mesenteric ischemia. J Vasc Surg. 2011;53(3):698–704. https://doi.org/10.1016/j.jvs.2010.09.049
15. Mizushima T, Udagawa E, Hasegawa M, Tazuke Y, Okuyama H, Fernandez J, Nakamura S. Etiologies and treatments of chronic intestinal failure-short bowel syndrome (SBS) in Japanese adults: a real-world observational study. Surg Today. 2022 Sep;52(9):1350–1357. https://doi.org/10.1007/s00595-022-02469-9
16. Harpain F, Schlager L, Hütterer E, Dawoud C, Kirchnawy S, Stift J, Krotka P, Stift A. Teduglutide in short bowel syndrome patients: A way back to normal life? JPEN J Parenter Enteral Nutr. 2022 Feb;46(2):300–309. https://doi.org/10.1002/jpen.2272
17. Tolonen M, Lemma A, Vikatmaa P, Peltola E, Mentula P, Björkman P, et al. The implementation of a pathway and care bundle for the management of acute occlusive arterial mesenteric ischemia reduced mortality. J Trauma Acute Care Surg. 2021 Sep 1;91(3):480–488. https://doi.org/10.1097/ta.0000000000003305
18. Tran LM, Andraska E, Haga L, Sridharan N, Chaer RA, Eslami MH. Hospital-based delays to revascularization increase risk of postoperative mortality and short bowel syndrome in acute mesenteric ischemia. J Vasc Surg. 2022 Apr;75(4):1323– 1333.e3. https://doi.org/10.1016/j.jvs.2021.09.033
Review
For citations:
Zelenin V.V., Soloviev I.A., Petrov A.A., Shcheglov D.S., Kudryavcev O.I., Akhmetov V.V., Dudanov I.P. Acute mesenteric ischemia: experience in the treatment of patients at a multidisciplinary hospital. Research and Practical Medicine Journal. 2026;13(3):95-102. (In Russ.) https://doi.org/10.17709/2410-1893-2026-13-3-6
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