THE USAGE OF "OCTREOTIDE-DEPOT" FOR THE PREVENTION OF POSTOPERATIVE PANCREATITIS AFTER EXTENDED SURGERY OF MALIGNANT TUMORS OF THE STOMACH, ESOPHAGUS AND THE CARDIA
https://doi.org/10.17709/2409-2231-2015-2-4-10-16
Abstract
Surgical treatment of patients with gastric cancer with extended lymph node dissection often leads to the primary (intra-operative injury) and secondary (inflammatory processes in the postoperative period) damage to the parenchyma of the pancreas. The incidence of pancreatitis in the postoperative period, according to various authors, reaches 20% or more. Synthetic analogues of somatostatin occupy the special place among the pharmacological methods of prophylaxis. Earlier studies have shown a significantly lower rate of complications, including the formation of pancreatic fistula after operations on the pancreas when using somatostatin analogues. Usage of prolonged SST analogues for the prevention of postoperative pancreatitis remains a matter of research. The article presents a review of existing literature and own experience with prophylactic use of «Оctreotide depot » in patients with malignant tumors of the stomach, esophagus and the cardia
About the Authors
V. M. Khomyakov
P. A. Hertsen Moscow Oncology Research Institute — branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
PhD, head of thoracoabdominal department, thoracoabdominal division P. A. Hertsen Moscow Oncology Research Institute — branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
A. V. Ivanov
P. A. Hertsen Moscow Oncology Research Institute — branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
postgraduate of thoracoabdominal department, thoracoabdominal division P. A. Hertsen Moscow Oncology Research Institute — branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
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Review
For citations:
Khomyakov V.M., Ivanov A.V. THE USAGE OF "OCTREOTIDE-DEPOT" FOR THE PREVENTION OF POSTOPERATIVE PANCREATITIS AFTER EXTENDED SURGERY OF MALIGNANT TUMORS OF THE STOMACH, ESOPHAGUS AND THE CARDIA. Research and Practical Medicine Journal. 2015;2(4):10-16. (In Russ.) https://doi.org/10.17709/2409-2231-2015-2-4-10-16
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